|
Posted by: Belliger on 2008-06-04, 13:09:19
Hello, I think this is a difficult question to answer. I can easily give you a list of the known, possible drug side-effects of methadone, - - they are the same as the morphine salts in general, viz. (from British National Formulary Sept 2007 edition, page 228, - - Side-effects: nausea, vomiting, (particularly in initial stages), constipation, and drowsiness. Larger doses: produce respiratory depression, hypotension, and muscle rigidity. Other side-effects: include difficulty with micturition, ureteric or biliary spasm, dry mouth, sweating, headache, facial flushing, vertigo, bradycardia, tachycardia, palpitation, postural hypotension, hypothermia, hallucination, dysphoria, mood changes, dependence, miosis, decreased libido or potency, rashes, urticaria, and pruritis. I'm assuming that you are not conversant with medicalese, so I will try to translate the relevant ones: low mood (dysphoria), mood changes, decreased sex drive, hallucinations of things that aren't there sometimes. (The others are related mostly to the bowels, the bladder, the heart, and the skin). It's difficult to answer because what you are describing may relate to the drug side-effects of methadone, or to his previous personality, or to other drugs he is still taking, ('go-go-go-crash' would be more common with amphetamines, cocaine or other stimulants or 'uppers' : methadone is not that much of a mental stimulant). Or he might have psychological trouble, and this 'everyone is against them' is what a doctor might call 'paranoia.' 'Very irritable' suggests he is wound up tight inside like a spring. I hope this is of some help. Best wishes, Belliger (retired uk gp) |